Adjusted Body Weight Formula:
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Adjusted Body Weight (AdjBW) is a calculated weight used primarily for medication dosing in obese patients. It accounts for the fact that adipose tissue has different pharmacokinetic properties than lean body mass.
The calculator uses the Adjusted Body Weight formula:
Where:
Explanation: This formula adjusts for excess adipose tissue by adding 40% of the difference between actual weight and ideal body weight to the ideal body weight.
Details: Adjusted body weight is particularly important for accurate dosing of medications that distribute differently in adipose tissue versus lean tissue. It helps prevent underdosing or overdosing in obese patients.
Tips: Enter ideal body weight and actual weight in kilograms. Both values must be positive numbers. The calculator will compute the adjusted body weight.
Q1: When should adjusted body weight be used?
A: AdjBW is typically used for medication dosing in obese patients (BMI > 30) for drugs that have limited distribution in adipose tissue.
Q2: How is ideal body weight calculated?
A: IBW can be calculated using various formulas, most commonly: for men: 50 kg + 2.3 kg per inch over 5 feet; for women: 45.5 kg + 2.3 kg per inch over 5 feet.
Q3: Are there alternatives to adjusted body weight?
A: Yes, other weight adjustments include total body weight, lean body weight, and dosing weight, depending on the specific medication and clinical scenario.
Q4: For which medications is adjusted body weight recommended?
A: AdjBW is commonly used for aminoglycosides, vancomycin, and some chemotherapeutic agents in obese patients.
Q5: What's the clinical significance of the 0.4 factor?
A: The 0.4 factor (40%) represents the estimated proportion of excess weight that should be considered for drug dosing, based on pharmacokinetic studies.