Adjusted Body Weight Formula:
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Adjusted Body Weight (AdjBW) is a calculation used for obese patients to estimate a more appropriate weight for medication dosing and nutritional assessments. It accounts for the fact that adipose tissue has different metabolic activity than lean body mass.
The calculator uses the Adjusted Body Weight formula:
Where:
Explanation: This formula adjusts for obesity by adding 40% of the difference between actual weight and ideal body weight to the ideal body weight.
Details: Adjusted body weight is particularly important for accurate medication dosing in obese patients, as many drugs are dosed based on weight but don't distribute equally into adipose tissue.
Tips: Enter ideal body weight and actual weight in kilograms. Both values must be positive numbers. The calculator is specifically designed for obese patients (typically those with BMI > 30 kg/m²).
Q1: When should I use adjusted body weight instead of actual weight?
A: Adjusted body weight should be used for medication dosing in obese patients, particularly for drugs that don't distribute well into adipose tissue.
Q2: How do I calculate ideal body weight?
A: Ideal body weight can be calculated using various formulas, most commonly: For men: 50 kg + 2.3 kg per inch over 5 feet; For women: 45.5 kg + 2.3 kg per inch over 5 feet.
Q3: For which medications is adjusted body weight typically used?
A: AdjBW is commonly used for dosing aminoglycosides, vancomycin, and some chemotherapeutic agents in obese patients.
Q4: What is the clinical significance of the 0.4 factor?
A: The 0.4 factor represents the estimated proportion of excess weight that should be considered for dosing calculations, based on pharmacokinetic studies.
Q5: Are there alternative methods for weight adjustment in obesity?
A: Yes, other methods include using total body weight for some drugs, lean body weight, or using specific obesity dosing guidelines provided in drug monographs.