Adjusted Body Weight Formula:
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Adjusted Body Weight (AdjBW) is a calculated weight used in clinical settings, particularly for medication dosing in obese patients. It accounts for the fact that adipose tissue has different pharmacokinetic properties than lean body mass.
The calculator uses the Adjusted Body Weight formula:
Where:
Explanation: This formula adjusts for the fact that adipose tissue has approximately 40% of the drug distribution capacity of lean tissue.
Details: Adjusted Body Weight is particularly important for accurate dosing of medications in obese patients, as using actual weight may lead to overdosing, while using ideal body weight may lead to underdosing.
Tips: Enter the patient's ideal body weight and actual weight in kilograms. Both values must be positive numbers.
Q1: When should Adjusted Body Weight be used?
A: AdjBW is typically used for medication dosing in obese patients (BMI > 30 kg/m²), particularly for drugs with narrow therapeutic windows.
Q2: How is Ideal Body Weight calculated?
A: IBW can be calculated using various formulas, most commonly: for men: 50 kg + 2.3 kg per inch over 5 feet; for women: 45.5 kg + 2.3 kg per inch over 5 feet.
Q3: Are there alternatives to the 0.4 correction factor?
A: Some medications or clinical scenarios may use different correction factors (e.g., 0.3 or 0.5) based on specific drug distribution characteristics.
Q4: Should AdjBW be used for all medications?
A: No, AdjBW is primarily used for certain antibiotics, chemotherapeutic agents, and other drugs where distribution differs significantly between lean and adipose tissue.
Q5: What's the difference between AdjBW and Lean Body Weight?
A: While both adjust for adipose tissue, Lean Body Weight is typically calculated differently and may be more appropriate for certain highly lipophilic drugs.